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Ru Zhou

Pfizer

24

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1073

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Multifaceted Substrate–Ligand Interactions Promote the Copper-Catalyzed Hydroboration of Benzylidenecyclobutanes and Related Compounds

2020 ChemRxiv
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Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR.

2017 Journal of Medicinal Chemistry
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Identification of novel pyrrolopyrazoles as protein kinase C β II inhibitors

2011 Bioorganic & Medicinal Chemistry Letters
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Pyridones as glucokinase activators: Identification of a unique metabolic liability of the 4-sulfonyl-2-pyridone heterocycle

2009 Bioorganic & Medicinal Chemistry Letters
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Fused fenylamidoheterocyclische compounds.

2007
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Composés phényle amido-hétérocycliques fusionnés pour la prévention et le traitement de maladies à médiation par glucokinase

2007
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Identification and structure-based optimization of novel dihydropyrones as potent HCV RNA polymerase inhibitors.

2006 Bioorganic & Medicinal Chemistry Letters
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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 6. Structure−Activity Studies of Orally Bioavailable, 2-Pyridone-Containing Peptidomimetics

2002 Journal of Medicinal Chemistry
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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. Part 7: Structure–Activity Studies of Bicyclic 2-Pyridone-Containing Peptidomimetics

2002 Bioorganic & Medicinal Chemistry Letters
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Anti-picornavirales compounds and compositions; pharmaceutical uses and materials used for its synthesis.

2000
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