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Shella A. Fuhrman

University of California, San Diego

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Development of a Novel Dicistronic Reporter-Selectable Hepatitis C Virus Replicon Suitable for High-Throughput Inhibitor Screening

2007 Antimicrobial Agents and Chemotherapy
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Allosteric inhibitors of hepatitis C polymerase: discovery of potent and orally bioavailable carbon-linked dihydropyrones.

2007 Journal of Medicinal Chemistry
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Crystal structure of the RNA-dependent RNA polymerase 3D from human rhinovirus serotype 14

2004
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Crystallographic Identification of a Noncompetitive Inhibitor Binding Site on the Hepatitis C Virus NS5B RNA Polymerase Enzyme

2003 Journal of Virology
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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 6. Structure−Activity Studies of Orally Bioavailable, 2-Pyridone-Containing Peptidomimetics

2002 Journal of Medicinal Chemistry
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Hepatitis C Virus (HCV) NS5B RNA Polymerase und davon abgeleitete Mutanten

2002
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Structure-based design of a parallel synthetic array directed toward the discovery of irreversible inhibitors of human rhinovirus 3C protease.

2002 Journal of Medicinal Chemistry
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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 3. Structure−Activity Studies of Ketomethylene-Containing Peptidomimetics

1999 Journal of Medicinal Chemistry
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Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 4. Incorporation of P1 lactam moieties as L-glutamine replacements.

1999 Journal of Medicinal Chemistry
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INTERACTION OF A NOVEL GDP EXCHANGE INHIBITOR WITH THE RAS PROTEIN

1998 Biochemistry
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