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T. Eric Ballard

North Carolina State University

18

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1216

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Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR.

2017 Journal of Medicinal Chemistry
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Development of Sulfonamide Photoaffinity Inhibitors for Probing Cellular γ-Secretase

2016 ACS Chemical Neuroscience
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Mechanism-Based Inactivation (MBI) of Cytochrome P450 Enzymes: Structure–Activity Relationships and Discovery Strategies To Mitigate Drug–Drug Interaction Risks

2012 Journal of Medicinal Chemistry
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Evaluation of dihydrooroidin as an antifouling additive in marine paint.

2009 International Biodeterioration & Biodegradation
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Antibiofilm activity of a diverse oroidin library generated through reductive acylation.

2009 Journal of Organic Chemistry
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Amide Isosteres of Oroidin: Assessment of Antibiofilm Activity and C. elegans Toxicity

2009 Journal of Medicinal Chemistry
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Inhibition and dispersion of Pseudomonas aeruginosa biofilms with reverse amide 2-aminoimidazole oroidin analogues

2008 Organic and Biomolecular Chemistry
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Synthesis and antibiofilm activity of a second-generation reverse-amide oroidin library: a structure-activity relationship study.

2008 Chemistry: A European Journal
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Inhibition and dispersion of proteobacterial biofilms

2008 Chemical Communications
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Synthesis and Screening of an Oroidin Library against Pseudomonas aeruginosa Biofilms

2008 ChemBioChem
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Citations (104)