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Michelle Bradley

Novartis

17

Papers

325

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Long Receptor Residence Time of C26 Contributes to Super Agonist Activity at the Human β2 Adrenoceptor

2016 Molecular Pharmacology
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Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action

2015 Molecular Pharmacology
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Investigating the molecular mechanisms through which FTY720-P causes persistent S1P1 receptor internalization.

2014 British Journal of Pharmacology
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QAW039, a slowly dissociating CRTh2 antagonist with potential for improved clinical efficacy

2014 Pharmacology
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The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting β2-adrenoceptor agonist

2014 Bioorganic & Medicinal Chemistry Letters
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The discovery of potent, orally bioavailable pyrazolo and triazolopyrimidine CXCR2 receptor antagonists.

2014 Bioorganic & Medicinal Chemistry Letters
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QAW039, a slowly dissociating CRTh2 antagonist with potential for improved clinical efficacy

2014 European Respiratory Journal
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An investigation into the structure–activity relationships associated with the systematic modification of the β2-adrenoceptor agonist indacaterol

2012 Bioorganic & Medicinal Chemistry Letters
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The in vitro metabolism of sphingosine-1-phosphate: Identification; inhibition and pharmacological implications

2011 European Journal of Pharmacology
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Design and synthesis of a library of chemokine antagonists.

2011 Bioorganic & Medicinal Chemistry Letters
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