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Thomas H. Keller

Agency for Science, Technology and Research
Novartis Institute for Tropical Diseases
Novartis

115

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4190

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Structure-activity relationship studies of allosteric inhibitors of EYA2 tyrosine phosphatase.

2021 Protein Science
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Targeting EYA2 tyrosine phosphatase activity in glioblastoma stem cells induces mitotic catastrophe.

2021 Journal of Experimental Medicine
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Fragment-based lead discovery of indazole-based compounds as AXL kinase inhibitors.

2021 Bioorganic & Medicinal Chemistry
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Intravenous transplantation of olfactory ensheathing cells reduces neuroinflammation after spinal cord injury via interleukin-1 receptor antagonist

2021 Theranostics
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Structural model of PORCN illuminates disease-associated variants and drug binding sites.

2021 Journal of Cell Science
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Structural model of PORCN illuminates disease-associated variants and drug binding sites

2021 bioRxiv
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Stepwise Evolution of Fragment Hits against MAPK Interacting Kinases 1 and 2

2020 Journal of Medicinal Chemistry
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Probing Biological Mechanisms with Chemical Tools

2020 Pharmacological Research
- CongBao Kang
- Thomas H. Keller
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Fragment-based Discovery of a Small-molecule Protein Kinase C-iota Inhibitor Binding Post-kinase Domain Residues

2019 ACS Medicinal Chemistry Letters
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Structural and ligand-binding analysis of the YAP-binding domain of transcription factor TEAD4

2018 Biochemical Journal
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Citations (21)