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Ragu Ramanathan

Pfizer

39

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810

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Identification of appropriate endogenous biomarker for risk assessment of multidrug and toxin extrusion protein-mediated drug-drug interactions in healthy volunteers.

2020 Clinical Pharmacology & Therapeutics
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A Multiplexed HILIC-MS/HRMS Assay for the Assessment of Transporter Inhibition Biomarkers in Phase I Clinical Trials: Isobutyryl-Carnitine as an Organic Cation Transporter (OCT1) Biomarker.

2020 Analytical Chemistry
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P231 - Study to assess the food effect on plasma levels of emerging endogenous biomarkers of transporter mediated drug-drug interactions

2020 Drug Metabolism and Pharmacokinetics
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Identification of Glycochenodeoxycholate 3‐O‐Glucuronide and Glycodeoxycholate 3‐O‐Glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers

2020 Clinical Pharmacology & Therapeutics
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2019 White Paper on Recent Issues in Bioanalysis: Chromatographic Assays (Part 1 – Innovation in Small Molecules and Oligonucleotides & Mass Spectrometric Method Development Strategies for Large Molecule Bioanalysis)

2019 Bioanalysis
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Simultaneous measurements of N1-methylnicotinamide, creatinine, isobutyryl-L-carnitine by liquid chromatograph with high resolution mass spectrometry for assessing the activities of multiple renal cationic transporters in first-in-human clinical trial

2019 Drug Metabolism and Pharmacokinetics
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A fully automated and validated human plasma LC–MS/MS assay for endogenous OATP biomarkers coproporphyrin-I and coproporphyrin-III

2018 Bioanalysis
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2018 White Paper on Recent Issues in Bioanalysis: ‘A global bioanalytical community perspective on last decade of incurred samples reanalysis (ISR)’ (Part 1 – small molecule regulated bioanalysis, small molecule biomarkers, peptides & oligonucleotide bioanalysis)

2018 Bioanalysis
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HPLC–high-resolution mass spectrometry with polarity switching for increasing throughput of human in vitro cocktail drug–drug interaction assay

2018 Bioanalysis
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2017 White Paper on recent issues in bioanalysis: aren't BMV guidance/guidelines ‘Scientific’? (Part 1 – LCMS: small molecules, peptides and small molecule biomarkers)

2017 Bioanalysis
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Citations (25)