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Charles Hottenstein

GlaxoSmithKline

17

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201

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Native high-resolution mass spectrometry analysis of noncovalent protein complexes up to 450 kDa.

2020 Bioanalysis
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Bioanalytical challenges and unique considerations to support pharmacokinetic characterization of bispecific biotherapeutics

2019 Bioanalysis
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2018 White Paper on Recent Issues in Bioanalysis: ‘A global bioanalytical community perspective on last decade of incurred samples reanalysis (ISR)’ (Part 1 – small molecule regulated bioanalysis, small molecule biomarkers, peptides & oligonucleotide bioanalysis)

2018 Bioanalysis
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Platforms and techniques used for biomarker assays: where are we now?

2017 Bioanalysis
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Ligand Binding Assays in the Regulated Bioanalytical Laboratory

2017
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Considerations and rationale for the selection of LC-MS/MS or ligand binding assays for bioanalysis of therapeutic proteins

2016
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2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV): (Part 3 - LBA, biomarkers and immunogenicity).

2016 Bioanalysis
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A whole-molecule immunocapture LC–MS approach for the in vivo quantitation of biotherapeutics

2016 Bioanalysis
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Assessment of the effect of ofatumumab on cardiac repolarization

2015 The Journal of Clinical Pharmacology
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Modulation of β-amyloid by a single dose of GSK933776 in patients with mild Alzheimer’s disease: a phase I study

2014 Alzheimer's Research & Therapy
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Citations (26)