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Surinder Kaur

Genentech

51

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IQ consortium perspective: complementary LBA and LC–MS in protein therapeutics bioanalysis and biotransformation assessment

2020 Bioanalysis
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Automated, Generic Reagent and Ultratargeted 2D-LC-MS/MSEnabling Quantification of Biotherapeutics and Soluble Targets downto pg/mL Range in Serum

2020 Analytical Chemistry
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2019 White Paper on Recent Issues in Bioanalysis: Chromatographic Assays (Part 1 – Innovation in Small Molecules and Oligonucleotides & Mass Spectrometric Method Development Strategies for Large Molecule Bioanalysis)

2019 Bioanalysis
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Antibody–Drug Conjugates Derived from Cytotoxic seco-CBI-Dimer Payloads Are Highly Efficacious in Xenograft Models and Form Protein Adducts In Vivo

2019 Bioconjugate Chemistry
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Method development of a novel PK assay for antibody-conjugated drug measurement of ADCs using peptide-linker drug analyte

2019 Analytical and Bioanalytical Chemistry
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Immunogenicity of antibody–drug conjugates: observations across eight molecules in eleven clinical trials

2019 Bioanalysis
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Optimizing hybrid LC–MS/MS binding conditions is critical: impact of biotransformation on quantification of trastuzumab

2018 Bioanalysis
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Modulating Antibody-Drug Conjugate Payload Metabolism by Conjugation Site and Linker Modification.

2018 Bioconjugate Chemistry
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Dosage multiplexé pour la quantification d'anticorps totaux et de médicaments conjugués à des anticorps

2017
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High-Resolution Accurate-Mass Mass Spectrometry Enabling In-Depth Characterization of in Vivo Biotransformations for Intact Antibody-Drug Conjugates

2017 Analytical Chemistry
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Citations (35)