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John Cook

Schering-Plough

15

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869

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Factor XIIa inhibition by Infestin-4: in vitro mode of action and in vivo antithrombotic benefit

2013 Thrombosis and Haemostasis
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Synthesis and Evaluation of Polycyclic Pyrazolo[3,4-d]pyrimidines as PDE1 and PDE5 cGMP Phosphodiesterase Inhibitors.

2010 ChemInform
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Ezetimibe improves high fat and cholesterol diet-induced non-alcoholic fatty liver disease in mice.

2008 European Journal of Pharmacology
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Discovery of novel orally active ureido NPY Y5 receptor antagonists

2008 Bioorganic & Medicinal Chemistry Letters
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Effects of a selective melanin-concentrating hormone 1 receptor antagonist on food intake and energy homeostasis in diet-induced obese mice

2006 European Journal of Pharmacology
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Discovery of orally efficacious melanin-concentrating hormone receptor-1 antagonists as antiobesity agents. Synthesis, SAR, and biological evaluation of bicyclo[3.1.0]hexyl ureas.

2006 Journal of Medicinal Chemistry
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Transgenic overexpression of neuromedin U promotes leanness and hypophagia in mice

2005 Journal of Endocrinology
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Meal Pattern Analysis of Diet‐Induced Obesity in Susceptible and Resistant Rats

2003 Obesity Research
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Fat Intake Affects Adiposity, Comorbidity Factors, and Energy Metabolism of Sprague-Dawley Rats

2002 Obesity Research
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Ezetimibe, a Potent Cholesterol Absorption Inhibitor, Normalizes Combined Dyslipidemia in Obese Hyperinsulinemic Hamsters

2001 Diabetes
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Citations (79)