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Dietmar Seiffert

Scripps Research Institute

59

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Factor XII full and partial null in rat confers robust antithrombotic efficacy with no bleeding.

2015 Blood Coagulation & Fibrinolysis
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Titrating haemophilia B phenotypes using siRNA strategy: evidence that antithrombotic activity is separated from bleeding liability

2015 Thrombosis and Haemostasis
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antagonist Roxifiban: implications for the etiology of thrombocytopenia of thrombocytopenia observed with the small molecule glycoprotein IIb/IIIa Prospective testing for drug-dependent antibodies reduces the incidence

2013
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Factor XIIa inhibition by Infestin-4: in vitro mode of action and in vivo antithrombotic benefit

2013 Thrombosis and Haemostasis
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is downregulated by smooth muscle cells Type 1 plasminogen activator inhibitor synthesis of endothelial cells

2011
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The Amyloid-β Rise and γ-Secretase Inhibitor Potency Depend on the Level of Substrate Expression

2008 Journal of Biological Chemistry
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Feedback activation of factor XI by thrombin does not occur in plasma

2007 Proceedings of the National Academy of Sciences of the United States of America
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Abnormalities in the fibrinolytic system of the vascular wall associated with atherosclerosis.

2006 Annals of the New York Academy of Sciences
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P2-122 Detection of Nβ peptide and quantitation of its inhibition by γ-secretase inhibitors

2004 Neurobiology of Aging
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Plasminogen has a broad extrahepatic distribution.

2002 Thrombosis and Haemostasis
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Citations (120)