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Jun Qin

Merck & Co.

15

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190

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Quality by design (QbD) of amide isosteres: 5,5-Disubstituted isoxazolines as potent CRTh2 antagonists with favorable pharmacokinetic and drug-like properties.

2014 Bioorganic & Medicinal Chemistry Letters
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The discovery of fused oxadiazepines as gamma secretase modulators for treatment of Alzheimer’s disease

2013 Bioorganic & Medicinal Chemistry Letters
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Discovery of a Potent Dihydrooxadiazole Series of Non-ATP-Competitive MK2 (MAPKAPK2) Inhibitors

2012 ACS Medicinal Chemistry Letters
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Cyclic Hydroxyamidines as Amide Isosteres: Discovery of Oxadiazolines and Oxadiazines as Potent and Highly Efficacious γ-Secretase Modulators in Vivo

2012 Journal of Medicinal Chemistry
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Discovery of fused 5,6-bicyclic heterocycles as γ-secretase modulators

2011 Bioorganic & Medicinal Chemistry Letters
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Discovery of a Potent Pyrazolopyridine Series of γ-Secretase Modulators

2011 ACS Medicinal Chemistry Letters
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The Discovery of Pyridone and Pyridazone Heterocycles as γ-Secretase Modulators

2010 ACS Medicinal Chemistry Letters
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Composés hétérocycliques contenant de l'azote et leurs procédés d'utilisation

2007
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Ortho-kondensierte 2-pyridinonderivate als agonisten des nikotinsäurerezeptors zur behandlung von dyslipidämie

2006
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Derives ortho-condenses de 2-pyridinone utilises comme agonistes du recepteur de l'acide nicotinique dans le traitement de la dyslipidemie

2006
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