author-photo

Fabrizio Fiore

Merck & Co.

21

Papers

947

Citations

Citation Trend

Filter By

Papers (15) Sort By

Journal Conference Others

Synthesis and antiviral properties of novel 7-heterocyclic substituted 7-deaza-adenine nucleoside inhibitors of Hepatitis C NS5B polymerase.

2012 Bioorganic & Medicinal Chemistry
Show All
- Source
- Cite
- Save
Citations (26)
a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus NS5B Polymerase

2011
Show All
- Source
- Cite
- Save
Citations (0)
Identification and SAR of novel pyrrolo[1,2-a]pyrazin-1(2H)-one derivatives as inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1).

2010 Bioorganic & Medicinal Chemistry Letters
Show All
- Source
- Cite
- Save
Citations (17)
Phosphoramidate prodrugs of 2'-C-methylcytidine for therapy of hepatitis C virus infection.

2009 Journal of Medicinal Chemistry
Show All
- Source
- Cite
- Save
Citations (44)
Synthesis and evaluation of novel phosphoramidate prodrugs of 2'-methyl cytidine as inhibitors of hepatitis C virus NS5B polymerase.

2009 Bioorganic & Medicinal Chemistry Letters
Show All
- Source
- Cite
- Save
Citations (26)
Discovery of a Potent Class I Selective Ketone Histone Deacetylase Inhibitor with Antitumor Activity in Vivo and Optimized Pharmacokinetic Properties

2009 Journal of Medicinal Chemistry
Show All
- Source
- Cite
- Save
Citations (38)
Metabolism-related liabilities of a potent histone deacetylase (HDAC) inhibitor and relevance of the route of administration on its metabolic fate

2009 Xenobiotica
Show All
- Source
- Cite
- Save
Citations (5)
Novel Macrocyclic Inhibitors of Hepatitis C NS3/4A Protease Featuring a 2-Amino-1,3-thiazole as a P4 Carbamate Replacement

2009 Journal of Medicinal Chemistry
Show All
- Source
- Cite
- Save
Citations (13)
Optimization of Thienopyrrole-Based Finger-Loop Inhibitors of the Hepatitis C Virus Ns5B Polymerase.

2009 ChemMedChem
Show All
- Source
- Cite
- Save
Citations (20)
Inhibitors of the Hepatitis C Virus NS3 Protease with Basic Amine Functionality at the P3-Amino Acid N-Terminus: Discovery and Optimization of a New Series of P2−P4 Macrocycles

2009 Journal of Medicinal Chemistry
Show All
- Source
- Cite
- Save
Citations (14)