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Christian Steinkühler

Merck & Co.

127

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The pan HDAC inhibitor Givinostat improves muscle function and histological parameters in two Duchenne muscular dystrophy murine models expressing different haplotypes of the LTBP4 gene.

2021 Skeletal Muscle
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Acute Kidney Injury Results in Long-Term Diastolic Dysfunction That Is Prevented by Histone Deacetylase Inhibition.

2021 JACC: Basic to Translational Science
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Role of Fluorination in the Histone Deacetylase 6 (HDAC6) Selectivity of Benzohydroxamate-Based Inhibitors.

2021 ACS Medicinal Chemistry Letters
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Abstract 15707: Histone Deacetylase Inhibition Reverses Preexisting Diastolic Dysfunction and Blocks Covert Extracellular Matrix Remodeling

2020 Circulation
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Synthesis and Biological Evaluation of RGD–Cryptophycin Conjugates for Targeted Drug Delivery

2019 Pharmaceutics
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Synthesis and Biological Evaluation of RGD and iso DGR–Monomethyl Auristatin Conjugates Targeting Integrin α V β 3

2019 ChemMedChem
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Octreotide Conjugates for Tumor Targeting and Imaging

2019 Pharmaceutics
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In Vivo Antitumor Activity of a Novel Acetazolamide–Cryptophycin Conjugate for the Treatment of Renal Cell Carcinomas

2018
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MK-4101 - a potent inhibitor of the hedgehog pathway - is highly active against medulloblastoma and basal cell carcinoma

2016 Molecular Cancer Therapeutics
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Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cells.

2013 Oncotarget
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