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Laura Llauger Bufi
Laura Llauger Bufi
Merck & Co.
Biochemistry
Chemistry
Smoothened
Poly ADP ribose polymerase
Biology
6
Papers
71
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N-(2-alkylaminoethyl)-4-(1,2,4-oxadiazol-5-yl)piperazine-1-carboxamides as highly potent smoothened antagonists.
2011
Bioorganic & Medicinal Chemistry Letters
Ester Muraglia
Jesus Maria Ontoria Ontoria
Danila Branca
Gabriella Dessole
Alberto Bresciani
Massimiliano Fonsi
Claudio Giuliano
Laura Llauger Bufi
Edith Monteagudo
Maria Cecilia Palumbi
Caterina Torrisi
Michael Rowley
Christian Steinkühler
Philip Jones
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Citations (22)
Development of substituted 6-[4-fluoro-3-(piperazin-1-ylcarbonyl)benzyl]-4,5-dimethylpyridazin-3(2H)-ones as potent poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors active in BRCA deficient cells.
2010
Bioorganic & Medicinal Chemistry Letters
Federica Ferrigno
Danila Branca
Olaf Kinzel
Samuele Lillini
Laura Llauger Bufi
Edith Monteagudo
Ester Muraglia
Michael Rowley
Carsten Schultz-Fademrecht
Carlo Toniatti
Caterina Torrisi
Philip Jones
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Citations (10)
Identification and SAR of novel pyrrolo[1,2-a]pyrazin-1(2H)-one derivatives as inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1).
2010
Bioorganic & Medicinal Chemistry Letters
Giovanna Pescatore
Danila Branca
Fabrizio Fiore
Olaf Kinzel
Laura Llauger Bufi
Ester Muraglia
Federica Orvieto
Michael Rowley
Carlo Toniatti
Caterina Torrisi
Philip Jones
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Citations (17)
Dérivés de pyridinone et de pyridazinone inhibiteurs de la poly(adp-ribose)polymérase (parp)
2007
Philip Jones
Olaf Kinzel
Giovanna Pescatore
Laura Llauger Bufi
Carsten Schultz-Fademrecht
Federica Ferrigno
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