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Sue-Ing Lin

Schering-Plough

25

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562

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Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity

2017 Journal of Medicinal Chemistry
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The discovery of N-((2H-tetrazol-5-yl)methyl)-4-((R)-1-((5r,8R)-8-(tert-butyl)-3-(3,5-dichlorophenyl)-2-oxo-1,4-diazaspiro[4.5]dec-3-en-1-yl)-4,4-dimethylpentyl)benzamide (SCH 900822): a potent and selective glucagon receptor antagonist.

2014 Journal of Medicinal Chemistry
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Piperazine‐Based CCR5 Antagonists as HIV‐1 Inhibitors. Part 1. 2(S)‐Methyl Piperazine as a Key Pharmacophore Element.

2010 ChemInform
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Tetrahydroquinoline sulfonamides as vasopressin 1b receptor anatgonists

2009 Bioorganic & Medicinal Chemistry Letters
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Piperazine-based CCR5 antagonists as HIV-1 inhibitors. III: synthesis, antiviral and pharmacokinetic profiles of symmetrical heteroaryl carboxamides ☆

2003 Bioorganic & Medicinal Chemistry Letters
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Piperazine-based CCR5 antagonists as HIV-1 inhibitors. I: 2(S)-methyl piperazine as a key pharmacophore element.

2001 Bioorganic & Medicinal Chemistry Letters
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Piperazine-Based CCR5 Antagonists as HIV-1 Inhibitors. II. Discovery of 1-[(2,4-Dimethyl-3-pyridinyl)carbonyl]-4- methyl-4-[3(S)-methyl-4-[1(S)-[4-(trifluoro- methyl)phenyl]ethyl]-1-piperazinyl]- piperidine N1-Oxide (Sch-350634), an Orally Bioavailable, Potent CCR5 Antagonist

2001 Journal of Medicinal Chemistry
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New Reactions of Hydrazides. Part 1. Directed ortho‐ and Lateral Metalation of Aromatic Carbocyclic and Heterocyclic Systems.

2000 ChemInform
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New reactions of hydrazides. Part 1: Directed ortho- and lateral metalation of aromatic carbocyclic and heterocyclic systems

1999 Tetrahedron Letters
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(−)-SCH 57939: synthesis and pharmacological properties of a potent, metabolically stable cholesterol absorption inhibitor

1996 Bioorganic & Medicinal Chemistry Letters
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Citations (23)