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Jeffrey T. Kohrt

Pfizer

31

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640

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Process Development of a Second Generation β-Amyloid-Cleaving Enzyme Inhibitor—Improving the Robustness of a Halogen-Metal Exchange Using Continuous Stirred-Tank Reactors

2021 Organic Process Research & Development
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Application of Flow and Biocatalytic Transaminase Technology for the Synthesis of a 1-Oxa-8-azaspiro[4.5]decan-3-amine

2021 Organic Process Research & Development
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Late-stage oxidative C(sp(3))-H methylation.

2020 Nature
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Oxidative diversification of amino acids and peptides by small-molecule iron catalysis

2016 Nature
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Highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase.

2013 Bioorganic & Medicinal Chemistry Letters
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Optimization of highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase

2013 Bioorganic & Medicinal Chemistry Letters
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Expedient synthesis of novel β-ketoesters from the Mizoroki–Heck coupling of ethyl 3-ethoxyacrylate with aryl and pyridyl halides

2013 Tetrahedron Letters
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Synthesis of Spiropiperidine Lactam Acetyl-CoA Carboxylase Inhibitors

2012 Journal of Organic Chemistry
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Novel and selective spiroindoline-based inhibitors of sky kinase

2012 Bioorganic & Medicinal Chemistry Letters
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Activation of the G-protein-coupled receptor 119: a conformation-based hypothesis for understanding agonist response.

2011 Journal of Medicinal Chemistry
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Citations (41)