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Daniel LaSala

Novartis

13

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357

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Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary MRSA Infections.

2021 Antimicrobial Agents and Chemotherapy
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Discovery of a Novel Piperidine-Based Inhibitor of Cholesteryl Ester Transfer Protein (CETP) That Retains Activity in Hypertriglyceridemic Plasma

2017 Journal of Medicinal Chemistry
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Discovery of N-[5-(6-Chloro-3-cyano-1-methyl-1H-indol-2-yl)-pyridin-3-ylmethyl]-ethanesulfonamide, a Cortisol-Sparing CYP11B2 Inhibitor that Lowers Aldosterone in Human Subjects

2015 Journal of Medicinal Chemistry
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Discovery of LFF269, a Cortisol-Sparing CYP11B2 Inhibitor that Lowers Aldosterone in Human Subjects

2015
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Aldosterone synthase inhibition: cardiorenal protection in animal disease models and translation of hormonal effects to human subjects

2014 Journal of Translational Medicine
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Discovery and in Vivo Evaluation of Potent Dual CYP11B2 (Aldosterone Synthase) and CYP11B1 Inhibitors

2013 ACS Medicinal Chemistry Letters
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Coexpression of CYP11B2 or CYP11B1 with adrenodoxin and adrenodoxin reductase for assessing the potency and selectivity of aldosterone synthase inhibitors

2009 Analytical Biochemistry
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Optimization of Halopemide for Phospholipase D2 inhibition

2007 Bioorganic & Medicinal Chemistry Letters
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When less is more: enhanced baculovirus production of recombinant proteins at very low multiplicities of infection.

1999 BioTechniques
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Characterization of recombinant human cathepsin B expressed at high levels in baculovirus

1998 Protein Science
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Citations (15)