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Ruben Tommasi

Novartis

49

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1690

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Pharmacokinetic/Pharmacodynamic Determination and Preclinical Pharmacokinetics of the β-Lactamase Inhibitor ETX1317 and Its Orally Available Prodrug ETX0282.

2020 ACS Infectious Diseases
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Discovery of an Orally Available Diazabicyclooctane Inhibitor (ETX0282) of Class A, C and D Serine β-lactamases.

2020 Journal of Medicinal Chemistry
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Role of the Klebsiella pneumoniae TolC porin in antibiotic efflux

2019 Research in Microbiology
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Scaffold Morphing To Identify Novel DprE1 Inhibitorswith Antimycobacterial Activity

2019 ACS Medicinal Chemistry Letters
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Antibacterial Drug Discovery: Some Assembly Required

2018 ACS Infectious Diseases
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Whole-Cell-Based Assay To Evaluate Structure Permeation Relationships for Carbapenem Passage through the Pseudomonas aeruginosa Porin OprD

2017 ACS Infectious Diseases
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Design, Synthesis, and Properties of a Potent Inhibitor of Pseudomonas aeruginosa Deacetylase LpxC.

2017 Journal of Medicinal Chemistry
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Acinetobacter baumannii OmpA Is a Selective Antibiotic Permeant Porin

2017 ACS Infectious Diseases
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Sulbactam Combined With the Novel β-lactamase Inhibitor ETX2514 for the Treatment of Multidrug-Resistant Acinetobacter baumannii Infections

2016 Open Forum Infectious Diseases
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Global Surveillance of the Activity of Sulbactam Combined With the Novel β-lactamase Inhibitor ETX2514 Against Clinical Isolates of Acinetobacter baumannii From 2014

2016 Open Forum Infectious Diseases
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