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Kun Liu

Merck & Co.

31

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667

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Discovery of IDO1 inhibitors containing a decahydroquinoline, decahydro-1,6-naphthyridine, or octahydro-1H-pyrrolo[3,2-c]pyridine scaffold.

2021 Bioorganic & Medicinal Chemistry Letters
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SAR towards indoline and 3-azaindoline classes of IDO1 inhibitors.

2021 Bioorganic & Medicinal Chemistry Letters
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Discovery of Amino-cyclobutarene-derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors for Cancer Immunotherapy

2019 ACS Medicinal Chemistry Letters
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Discovery of MK-8719, a Potent O-GlcNAcase Inhibitor as a Potential Treatment for Tauopathies

2019 Journal of Medicinal Chemistry
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Discovery of novel non-steroidal reverse indole mineralocorticoid receptor antagonists.

2016 Bioorganic & Medicinal Chemistry Letters
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Low-Energy Solvents for Carbon Dioxide Capture Enabled by a Combination of Enzymes and Vacuum Regeneration

2015
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Benzimidazolones: A New Class of Selective Peroxisome Proliferator-Activated Receptor γ (PPARγ) Modulators

2011 Journal of Medicinal Chemistry
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Synthesis of 5,6-Dihydro-4-hydroxy-2-pyrones via Formal Cycloaddition Reactions.

2010 ChemInform
- Kun Liu
- L. Xu
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Discovery of (2R)-2-(3-{3-[(4-Methoxyphenyl)carbonyl]-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl}phenoxy)butanoic Acid (MK-0533): A Novel Selective Peroxisome Proliferator-Activated Receptor γ Modulator for the Treatment of Type 2 Diabetes Mellitus with a Reduced Potential to Increase Plasma and Extracellular Fluid Volume

2009 Journal of Medicinal Chemistry
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Discovery of a Peroxisome Proliferator Activated Receptor γ (PPARγ) Modulator with Balanced PPARα Activity for the Treatment of Type 2 Diabetes and Dyslipidemia

2009 Journal of Medicinal Chemistry
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Citations (20)