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Anand Selvaraj

18

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Phase I study of H3B-6527 in hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma (ICC).

2021 Journal of Clinical Oncology
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Abstract 2334: Discovery of selective inhibitors of carbamoyl phosphate synthetase I (CPS1) to modulate cancer relevant metabolic pathways

2021
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Discovery of Aminopyrazole Derivatives as Potent Inhibitors of Wild-Type and Gatekeeper Mutant FGFR2 and 3

2020 ACS Medicinal Chemistry Letters
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Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket

2020 Chemistry & Biology
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The R882H DNMT3A hotspot mutation stabilizes the formation of large DNMT3A oligomers with low DNA methyltransferase activity

2019 Journal of Biological Chemistry
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POLYTHÉRAPIES POUR LE TRAITEMENT DU CARCINOME HÉPATOCELLULAIRE

2018
- Anand Selvaraj
- P.G.R. Smith
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Abstract 3126: H3B6527, a selective and potent FGFR4 inhibitor for FGF19-driven hepatocellular carcinoma

2017 Cancer Research
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Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3′ Splice Site Selection through Use of a Different Branch Point

2015 Cell Reports
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FGFR4 inhibitors pyrimidine

2014
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Abstract 2932: SF3B1 mutations induce aberrant mRNA splicing in cancer and confer sensitivity to spliceosome inhibition

2014 Cancer Research
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