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Shihua Yao

16

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272

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Abstract 2334: Discovery of selective inhibitors of carbamoyl phosphate synthetase I (CPS1) to modulate cancer relevant metabolic pathways

2021
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Abstract PS12-23: Development of H3B-6545, a first-in-class oral selective ER covalent antagonist (SERCA), for the treatment of ERaWT and ERaMUT breast cancer

2021 Cancer Research
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Discovery of Aminopyrazole Derivatives as Potent Inhibitors of Wild-Type and Gatekeeper Mutant FGFR2 and 3

2020 ACS Medicinal Chemistry Letters
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Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket

2020 Chemistry & Biology
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Discovery of 2,6-Dimethylpiperazines as Allosteric Inhibitors of CPS1

2020 ACS Medicinal Chemistry Letters
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The R882H DNMT3A hotspot mutation stabilizes the formation of large DNMT3A oligomers with low DNA methyltransferase activity

2019 Journal of Biological Chemistry
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Lymph node metastasis in thymic malignancies: A Chinese multicenter prospective observational study

2018 The Journal of Thoracic and Cardiovascular Surgery
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Abstract A20: A leukemic model of acquired resistance to BET inhibition reveals a role for CBP/EP300 bromodomains in the regulation of c-MYC expression

2015 Molecular Cancer Research
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Incidence and risk factors for acute lung injury after open thoracotomy for thoracic diseases

2013 Journal of Thoracic Disease
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Kinetic characterization of recombinant human acidic mammalian chitinase.

2006 Biochemistry
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