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Ping Zhu

Novartis

46

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1889

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Sensitivity to splicing modulation of BCL2 family genes defines cancer therapeutic strategies for splicing modulators

2019 Nature Communications
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Coupling multiplex pre-amplification and droplet digital PCR for longitudinal monitoring of ESR1 and PIK3CA mutations from plasma cell-free DNA

2019 bioRxiv
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Estrogen Receptor Covalent Antagonists: The Best Is Yet to Come

2019 Cancer Research
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H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers

2018 Nature Medicine
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VARIANTS D'ÉPISSAGE ASSOCIÉS À DES MUTANTS DE SF3B1 NÉOMORPHES

2017
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Abstract P3-04-26: Establishment and characterization of ST941/C; an ESR1-mutant ER+ breast cancer cell line and xenograft from a patient with acquired resistance to endocrine therapy

2017 Cancer Research
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Loss of function JAK1 mutations occur at high frequency in cancers with microsatellite instability and are suggestive of immune evasion

2017 PLOS ONE
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Characterization of Novel Oral Splicing Modulator, H3B-8800, Identifies the Mechanistic Basis for its Preferential Lethality Towards Spliceosome-Mutant Myeloid Malignancy Models

2017 Leukemia Research
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Abstract 1185: H3B-8800, a novel orally available SF3b modulator, shows preclinical efficacy across spliceosome mutant cancers

2017 Cancer Research
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Development of selective MELK kinase inhibitors for breast cancer treatment

2016 European Journal of Cancer
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