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Hartmut Jahns
Hartmut Jahns
Alnylam Pharmaceuticals
In vivo
RNA interference
Small interfering RNA
Biology
Stereochemistry
2
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Chirality matters: stereo-defined phosphorothioate linkages at the termini of small interfering RNAs improve pharmacology in vivo.
2021
Nucleic Acids Research
Hartmut Jahns
Nate Taneja
Jennifer L. S. Willoughby
Masaaki Akabane-Nakata
Christopher R. Brown
Tuyen Nguyen
Anna Bisbe
Shigeo Matsuda
Matt Hettinger
Rajar M. Manoharan
Kallanthottathil G. Rajeev
Martin Maier
Ivan Zlatev
Klaus Charisse
Martin Egli
Muthiah Manoharan
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Small circular interfering RNAs (sciRNAs) as a potent therapeutic platform for gene-silencing.
2021
Nucleic Acids Research
Hartmut Jahns
Rohan Degaonkar
Peter Podbevšek
Swati Gupta
Anna Bisbe
Krishna Aluri
John Szeto
Pawan Kumar
Sarah Leblanc
Tim Racie
Christopher R. Brown
Adam Castoreno
Dale C Guenther
Vasant Jadhav
Martin Maier
Janez Plavec
Martin Egli
Muthiah Manoharan
Ivan Zlatev
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