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Stanley F. Barnett

Merck & Co.

19

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1717

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Entidades quimicas simples novedosas y metodos de suministro de oligonucleotidos.

2011
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Quantitative evaluation of siRNA delivery in vivo

2010 RNA
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Allosteric inhibitors of Akt1 and Akt2: discovery of [1,2,4]triazolo[3,4-f][1,6]naphthyridines with potent and balanced activity.

2009 Bioorganic & Medicinal Chemistry Letters
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Development of potent, allosteric dual Akt1 and Akt2 inhibitors with improved physical properties and cell activity.

2008 Bioorganic & Medicinal Chemistry Letters
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The PI3K/Akt pathway: recent progress in the development of ATP-competitive and allosteric Akt kinase inhibitors.

2008 Current Cancer Drug Targets
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Allosteric inhibitors of Akt1 and Akt2: a naphthyridinone with efficacy in an A2780 tumor xenograft model.

2008 Bioorganic & Medicinal Chemistry Letters
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The design and synthesis of potent and cell-active allosteric dual Akt 1 and 2 inhibitors devoid of hERG activity

2008 Bioorganic & Medicinal Chemistry Letters
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Optimization of 2,3,5-trisubstituted pyridine derivatives as potent allosteric Akt1 and Akt2 inhibitors

2008 Bioorganic & Medicinal Chemistry Letters
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Rapid assembly of diverse and potent allosteric Akt inhibitors.

2008 Bioorganic & Medicinal Chemistry Letters
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Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors.

2005 Bioorganic & Medicinal Chemistry Letters
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Citations (436)