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Tony Siu

Merck & Co.

18

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158

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Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING

2019 ACS Medicinal Chemistry Letters
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The Discovery of 3-((4-Chloro-3-methoxyphenyl)amino)-1-((3R,4S)-4-cyanotetrahydro-2H-pyran-3-yl)-1H-pyrazole-4-carboxamide, a Highly Ligand Efficient and Efficacious Janus Kinase 1 Selective Inhibitor with Favorable Pharmacokinetic Properties

2017 Journal of Medicinal Chemistry
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Composés de di-nucléotide cyclique en tant qu'agonistes sting (stimulateur de gène interféron)

2016
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Structure-based design and development of (benz)imidazole pyridones as JAK1-selective kinase inhibitors

2016 Bioorganic & Medicinal Chemistry Letters
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Inhibiteurs de la btk de type indazole et azaindazole

2015
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The discovery of reverse tricyclic pyridone JAK2 inhibitors. Part 2: Lead optimization

2014 Bioorganic & Medicinal Chemistry Letters
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Dérivés de pyrazolyle en tant qu'inhibiteurs de syk

2013
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Aminopyrimidine als syk-hemmer

2010
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Aminopyrimidines as inhibitors of Syk

2010
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Inhibiteurs de pyrazolo[3,4-b]pyridin-4-one kinase

2010
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