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Olaf H. Temmink

VU University Medical Center

14

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525

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Trifluorothymidine Resistance Is Associated with Decreased Thymidine Kinase and Equilibrative Nucleoside Transporter Expression or Increased Secretory Phospholipase A2

2010 Molecular Cancer Therapeutics
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Activity and substrate specificity of pyrimidine phosphorylases and their role in fluoropyrimidine sensitivity in colon cancer cell lines.

2007 The International Journal of Biochemistry & Cell Biology
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The hollow fibre assay as a model for in vivo pharmacodynamics of fluoropyrimidines in colon cancer cells

2007 British Journal of Cancer
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Role of platelet derived endothelial cell growth factor / thymidine phosphorylase in health and diseaseArticle

2006
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Low folate conditions may enhance the interaction of trifluorothymidine with antifolates in colon cancer cells

2006 Cancer Chemotherapy and Pharmacology
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The role of thymidine phosphorylase and uridine phosphorylase in (fluoro)pyrimidine metabolism in peripheral blood mononuclear cells

2006 The International Journal of Biochemistry & Cell Biology
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Determinants of trifluorothymidine sensitivity and metabolism in colon and lung cancer cells.

2005 Anti-Cancer Drugs
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Intracellular Thymidylate Synthase Inhibition by Trifluorothymidine in FM3A Cells

2004 Nucleosides, Nucleotides & Nucleic Acids
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Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression

2003 Biochemical Pharmacology
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Citations (126)