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Nienke Losekoot

VU University Medical Center

13

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292

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Metabolism, mechanism of action and sensitivity profile of fluorocyclopentenylcytosine (RX-3117; TV-1360)

2013 Investigational New Drugs
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Folate homeostasis of cancer cells affects sensitivity to not only antifolates but also other non-folate drugs: effect of MRP expression

2013 Pteridines
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The effect of allopurinol and low-dose thiopurine combination therapy on the activity of three pivotal thiopurine metabolizing enzymes: Results from a prospective pharmacological study

2013 Journal of Crohns & Colitis
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Metabolism and accumulation of the lipophilic deoxynucleoside analogs elacytarabine and CP-4126

2012 Investigational New Drugs
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Abstract 3785: Human pharmacokinetics (PK) of selected tyrosine kinase inhibitors (TKI) in relation to transport characteristics in a polarized gut epithelium model system

2012 Cancer Research
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Cellular pharmacology of multi- and duplex drugsconsisting of ethynylcytidine and 5-fluoro-2 '-deoxyuridine

2011 Investigational New Drugs
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Trifluorothymidine Resistance Is Associated with Decreased Thymidine Kinase and Equilibrative Nucleoside Transporter Expression or Increased Secretory Phospholipase A2

2010 Molecular Cancer Therapeutics
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Induction of Resistance to the Lipophilic Cytarabine Prodrug Elacytarabine (CP-4055) in CEM Leukemic Cells

2010 Nucleosides, Nucleotides & Nucleic Acids
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Simple and selective method for the determination of various tyrosine kinase inhibitors used in the clinical setting by liquid chromatography tandem mass spectrometry

2010 Journal of Chromatography B
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Oxaliplatin activity in selected and unselected human ovarian and colorectal cancer cell lines.

2008 Biochemical Pharmacology
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Citations (37)