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Michael D. Waterfield

Ludwig Institute for Cancer Research
University College London

138

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Targeting PI3KC2β Impairs Proliferation and Survival in Acute Leukemia, Brain Tumours and Neuroendocrine Tumours

2012 Anticancer Research
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Major Role of Epidermal Growth Factor Receptor and Src Kinases in Promoting Oxidative Stress-dependent Loss of Adhesion and Apoptosis in Epithelial Cells

2010 Journal of Biological Chemistry
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Phosphoproteomic analysis of oxidative stress in mammary epithelial cells: Major role of Src kinase-dependent phosphorylation in regulating adhesion

2010 F1000Research
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mTORβ Splicing Isoform Promotes Cell Proliferation and Tumorigenesis

2009 Journal of Biological Chemistry
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Alternative modes of binding of proteins with tandem SH2 domains

2008 Protein Science
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Structural analysis of PI3-kinase isoforms: Identification of residues enabling selective inhibition by small molecule ATP-competitive inhibitors

2008 Archives of Biochemistry and Biophysics
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A selective PIKfyve inhibitor blocks PtdIns(3,5)P2 production and disrupts endomembrane transport and retroviral budding

2008 EMBO Reports
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Synthesis and biological evaluation of sulfonylhydrazone-substituted imidazo[1,2 -a]pyridines as novel PI3 kinase p110α inhibitors

2007 Bioorganic & Medicinal Chemistry
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Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110α inhibitors

2007 Bioorganic & Medicinal Chemistry
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Gene and Protein Expression Profiling of Human Ovarian Cancer Cells Treated with the Heat Shock Protein 90 Inhibitor 17-Allylamino-17-Demethoxygeldanamycin

2007 Cancer Research
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Citations (123)