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Ming-Hong Hao

Boehringer Ingelheim

30

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Abstract PS12-23: Development of H3B-6545, a first-in-class oral selective ER covalent antagonist (SERCA), for the treatment of ERaWT and ERaMUT breast cancer

2021 Cancer Research
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Synthesis, SAR, and series evolution of novel oxadiazole-containing 5-lipoxygenase activating protein inhibitors: discovery of 2-[4-(3-{(r)-1-[4-(2-amino-pyrimidin-5-yl)-phenyl]-1-cyclopropyl-ethyl}-[1,2,4]oxadiazol-5-yl)-pyrazol-1-yl]-N,N-dimethyl-acetamide (BI 665915).

2015 Journal of Medicinal Chemistry
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Discovery of Potent, Selective Chymase Inhibitors via Fragment Linking Strategies

2013 Journal of Medicinal Chemistry
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Efficient Chiral Monophosphorus Ligands for Asymmetric Suzuki–Miyaura Coupling Reactions

2012 Organic Letters
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Benzimidazolone as potent chymase inhibitor: modulation of reactive metabolite formation in the hydrophobic (P1) region.

2011 Bioorganic & Medicinal Chemistry Letters
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Inhibiteurs de chymase

2009
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The discovery of thienopyridine analogues as potent IκB kinase β inhibitors. Part II

2009 Bioorganic & Medicinal Chemistry Letters
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Inhibiteurs de benzimidazolone chymase

2008
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Structure-based design and subsequent optimization of 2-tolyl-(1,2,3-triazol-1-yl-4-carboxamide) inhibitors of p38 MAP kinase

2008 Bioorganic & Medicinal Chemistry Letters
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Synthesis and SAR studies of indole-based MK2 inhibitors

2008 Bioorganic & Medicinal Chemistry Letters
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Citations (34)