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Victor Certal

10

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Preparation and optimization of new 4-(2-(indolin-1-yl)-2-oxoethyl)-2-morpholinothiazole-5-carboxylic acid and amide derivatives as potent and selective PI3Kβ inhibitors

2014 Bioorganic & Medicinal Chemistry Letters
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Discovery and optimization of new benzimidazole- and benzoxazole-pyrimidone selective PI3Kβ inhibitors for the treatment of phosphatase and TENsin homologue (PTEN)-deficient cancers.

2012 Journal of Medicinal Chemistry
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Preparation and optimization of new 4-(morpholin-4-yl)-(6-oxo-1,6-dihydropyrimidin-2-yl)amide derivatives as PI3Kβ inhibitors.

2012 Bioorganic & Medicinal Chemistry Letters
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Novel (6-oxo-1,6-dihydro-pyrimidin-2-yl) -amidderivater, the preparation thereof and pharmaceutical use thereof as Akt-phosphoryleringshæmmere

2010
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NOVEL 1h-pyrimidin-2-one, their pharmaceutical preparation as phosphorylation inhibitors of Akt (PKB)

2009
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NOVEL 1h-pyrimidin-2-one, their preparation and their pharmaceutical use as inhibitors of phosphorylation of Akt (PKB)

2009
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New derivatives of carbazole of hsp90 inhibitors, compositions containing them and use

2008
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Sulphurs novel cyclic urea, their preparation and their pharmaceutical use as kinase inhibitors

2006
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Novel cyclic urea, their preparation and their pharmaceutical use as kinase inhibitors

2006
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