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Karthik Narsimhan
Karthik Narsimhan
Merck & Co.
Chemistry
sustainable manufacturing
Materials science
continuous flow
P2X3 Receptor
5
Papers
30
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Manufacturing Process Development for Belzutifan, Part 2: A Continuous Flow Visible-Light-Induced Benzylic Bromination
2021
Organic Process Research & Development
Cecilia Bottecchia
François Lévesque
Jonathan P. McMullen
Yining Ji
Mikhail Reibarkh
Feng Peng
Lushi Tan
Glenn Spencer
Jarod Nappi
Dan Lehnherr
Karthik Narsimhan
Michael K. Wismer
Like Chen
Yipeng Lin
Stephen M. Dalby
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Citations (6)
Benzylic Photobromination for the Synthesis of Belzutifan: Elucidation of Reaction Mechanisms Using In Situ LED-NMR.
2021
Journal of Organic Chemistry
Yining Ji
Cecilia Bottecchia
François Lévesque
Karthik Narsimhan
Dan Lehnherr
Jonathan P. McMullen
Stephen M. Dalby
Kai-Jiong Xiao
Mikhail Reibarkh
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Citations (2)
Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 2: Development of a Robust Process for Phenol Synthesis
2020
Organic Process Research & Development
Feng Peng
Guy R. Humphrey
Kevin M. Maloney
Dan Lehnherr
Mark Weisel
François Lévesque
John R. Naber
Andrew Brunskill
Patrick Larpent
Si-Wei Zhang
Alfred Y. Lee
Rebecca A. Arvary
Claire Lee
Daniel Bishara
Karthik Narsimhan
Eric Sirota
Michael Whittington
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Citations (5)
Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264). Part 5: Completion of the API Free Base via a Direct Chlorosulfonylation Process
2020
Organic Process Research & Development
Michael J. Di Maso
Hong Ren
Si-Wei Zhang
Wenjun Liu
Richard Desmond
Embarek Alwedi
Karthik Narsimhan
Alexei Kalinin
Patrick Larpent
Alfred Y. Lee
Sumei Ren
Kevin M. Maloney
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Citations (6)
Design of a Kilogram Scale, Plug Flow Photoreactor Enabled by High Power LEDs
2020
Organic Process Research & Development
François Lévesque
Michael J. Di Maso
Karthik Narsimhan
Michael K. Wismer
John R. Naber
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Citations (11)
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