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Patrick Larpent
Patrick Larpent
Merck & Co.
sustainable manufacturing
Chemistry
Pulp and paper industry
Combinatorial chemistry
salt formation
4
Papers
20
Citations
0
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Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 3: Development of a One-Pot Formylation–Cyclization Sequence to the Diaminopyrimidine Core
2020
Organic Process Research & Development
Kallol Basu
Dan Lehnherr
Gary E. Martin
Richard Desmond
Yu-hong Lam
Feng Peng
John Y. L. Chung
Rebecca A. Arvary
Michael A. Zompa
Si-Wei Zhang
Jinchu Liu
Zachary E. X. Dance
Patrick Larpent
Ryan D. Cohen
Francisco J. Guzman
Nicholas J. Rogus
Michael J. Di Maso
Hong Ren
Kevin M. Maloney
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Citations (5)
Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 2: Development of a Robust Process for Phenol Synthesis
2020
Organic Process Research & Development
Feng Peng
Guy R. Humphrey
Kevin M. Maloney
Dan Lehnherr
Mark Weisel
François Lévesque
John R. Naber
Andrew Brunskill
Patrick Larpent
Si-Wei Zhang
Alfred Y. Lee
Rebecca A. Arvary
Claire Lee
Daniel Bishara
Karthik Narsimhan
Eric Sirota
Michael Whittington
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Citations (5)
Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264). Part 5: Completion of the API Free Base via a Direct Chlorosulfonylation Process
2020
Organic Process Research & Development
Michael J. Di Maso
Hong Ren
Si-Wei Zhang
Wenjun Liu
Richard Desmond
Embarek Alwedi
Karthik Narsimhan
Alexei Kalinin
Patrick Larpent
Alfred Y. Lee
Sumei Ren
Kevin M. Maloney
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Citations (6)
Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264). Part 6: Development of an Improved Commercial Salt Formation Process
2020
Organic Process Research & Development
Kevin M. Maloney
Si-Wei Zhang
Anne E. Mohan
Alfred Y. Lee
Patrick Larpent
Hong Ren
Guy R. Humphrey
Richard Desmond
Michael DiBenedetto
Wenjun Liu
Ivan Hao Lee
Eric Sirota
Michael J. Di Maso
Embarek Alwedi
Siqing Song
Hsieh Yao D. Chang
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Citations (4)
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