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Andres Salmeron

National Institute for Medical Research

14

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722

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715 WTX-330 is an IL-12 pro-drug that is conditionally activated within the tumor microenvironment and induces regressions in mouse tumor models

2021 Journal for ImmunoTherapy of Cancer
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Abstract 1723: WTX-124 is an IL-2 pro-drug conditionally activated in tumors and able to induce complete regressions in mouse tumor models

2021 Immunology
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718 WTX-124 is a novel IL-2 pro-drug that is conditionally activated in tumors and drives antitumor immunity in murine syngeneic cancer models

2021 Journal for ImmunoTherapy of Cancer
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Abstract 1716: WTX-330, a conditionally activated IL-12 INDUKINE, releases IL-12 selectively in the tumor microenvironment to activate anti-tumor immune responses and induce regressions in mouse tumor models

2021 Immunology
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Conditionally Activated IL-12 or IFNα Indukine™ Molecules Inhibit Syngeneic Lymphoma Tumor Growth in Mice, Induce Anti-Tumor Immune Responses and Are Tolerated in Non-Human Primates

2021 Blood
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723 WTX-613, a conditionally activated IFNα INDUKINE™ molecule, induces anti-tumor immune responses resulting in strong tumor growth control in syngeneic mouse tumor models

2021 Journal for ImmunoTherapy of Cancer
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Bromodomain and Extra-Terminal Protein Inhibition Attenuates Neutrophil-dominant Allergic Airway Disease

2017 Scientific Reports
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Regulatory T Cell Modulation by CBP/EP300 Bromodomain Inhibition

2016 Journal of Biological Chemistry
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BET bromodomain inhibition suppresses TH17-mediated pathology

2013 Journal of Experimental Medicine
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Identification of a selective thieno[2,3-c]pyridine inhibitor of COT kinase and TNF-α production

2009 Bioorganic & Medicinal Chemistry Letters
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Citations (21)