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Daniel J. Hicklin

ImClone Systems
Eli Lilly and Company
Merck & Co.

246

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42267

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715 WTX-330 is an IL-12 pro-drug that is conditionally activated within the tumor microenvironment and induces regressions in mouse tumor models

2021 Journal for ImmunoTherapy of Cancer
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Abstract 1723: WTX-124 is an IL-2 pro-drug conditionally activated in tumors and able to induce complete regressions in mouse tumor models

2021 Immunology
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718 WTX-124 is a novel IL-2 pro-drug that is conditionally activated in tumors and drives antitumor immunity in murine syngeneic cancer models

2021 Journal for ImmunoTherapy of Cancer
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Conditionally Activated IL-12 or IFNα Indukine™ Molecules Inhibit Syngeneic Lymphoma Tumor Growth in Mice, Induce Anti-Tumor Immune Responses and Are Tolerated in Non-Human Primates

2021 Blood
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Characterization of ASP8374, a fully-human, antagonistic anti-TIGIT monoclonal antibody.

2021 Cancer treatment and research
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Abstract 2727: The discovery and characterization of PTZ-201, a fully-human, high affinity, antagonistic anti-TIGIT monoclonal antibody

2018 Cancer Research
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Polythérapies comprenant des molécules d'anticorps contre tim -3

2016
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Discovery of Novel 3,3-Disubstituted Piperidines as Orally Bioavailable, Potent, and Efficacious HDM2-p53 Inhibitors.

2016 ACS Medicinal Chemistry Letters
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Protéines de liaison à un antigène anti-tigit et leurs méthodes d'utilisation

2016
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Kombinationstherapien mit antikörpermolekülen gegen lag-3

2016
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