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F. Anthony Romero

Merck & Co.

39

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Preclinical Safety Assessment of a Highly Selective and Potent Dual Small-Molecule Inhibitor of CBP/P300 in Rats and Dogs:

2020 Toxicologic Pathology
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Fragment-Based Lead Discovery of a Novel Class of Small Molecule Inhibitors of Neuropeptide B/W Receptor Subtype 1 (GPR7)

2020 Bioorganic & Medicinal Chemistry Letters
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The Race to Bash NASH: Emerging Targets and Drug Development in a Complex Liver Disease

2020 Journal of Medicinal Chemistry
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Regulation of Tumor-Associated Myeloid Cell Activity by CBP/EP300 Bromodomain Modulation of H3K27 Acetylation

2019 Cell Reports
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CBP/p300 drives the differentiation of Regulatory T cells through transcriptional and non-transcriptional mechanisms

2019 Cancer Research
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Optimization of Preclinical Metabolism for Somatostatin Receptor Subtype 5-Selective Antagonists

2018 ACS Medicinal Chemistry Letters
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Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation

2018 Cell Reports
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Design and synthesis of a biaryl series as inhibitors for the bromodomains of CBP/P300.

2018 Bioorganic & Medicinal Chemistry Letters
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Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase

2018 ACS Medicinal Chemistry Letters
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Therapeutic Targeting of the CBP/p300 Bromodomain Blocks the Growth of Castration-Resistant Prostate Cancer.

2017 Cancer Research
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