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Sara H. Thrall

GlaxoSmithKline

27

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1049

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Transition state for the NSD2-catalyzed methylation of histone H3 lysine 36

2016 Proceedings of the National Academy of Sciences of the United States of America
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Mutant IDH1 Enhances the Production of 2-Hydroxyglutarate Due to Its Kinetic Mechanism.

2013 Biochemistry
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Perspectives on the Discovery of Small-Molecule Modulators for Epigenetic Processes

2012 Journal of Biomolecular Screening
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Development and Validation of Reagents and Assays for EZH2 Peptide and Nucleosome High-Throughput Screens

2012 Journal of Biomolecular Screening
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Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)

2012 Proceedings of the National Academy of Sciences of the United States of America
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Understanding the origins of time-dependent inhibition by polypeptide deformylase inhibitors.

2011 Biochemistry
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Methyltransferases prefer monomer over core-trimmed nucleosomes as in vitro substrates.

2011 Analytical Biochemistry
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Kinetic Mechanism and Rate-Limiting Steps of Focal Adhesion Kinase-1

2010 Biochemistry
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Chemical Mechanism of a Cysteine Protease, Cathepsin C, As Revealed by Integration of both Steady-State and Pre-Steady-State Solvent Kinetic Isotope Effects

2008 Biochemistry
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A High-Throughput Screen for Endothelial Lipase Using HDL as Substrate

2008 Journal of Biomolecular Screening
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Citations (16)