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Glenn A. Hofmann

GlaxoSmithKline

46

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Development of a High-Throughput Cul3-Keap1 Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) Assay for Identifying Nrf2 Activators:

2019
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Screen for modulators of atonal homolog 1 gene expression using notch pathway-relevant gene transcription based cellular assays

2018 PLOS ONE
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High throughput screening identifies ATP-competitive inhibitors of the NLRP1 inflammasome

2015 Bioorganic & Medicinal Chemistry Letters
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Selective class IIa histone deacetylase inhibition via a nonchelating zinc-binding group

2013 Nature Chemical Biology
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Development and Validation of Reagents and Assays for EZH2 Peptide and Nucleosome High-Throughput Screens

2012 Journal of Biomolecular Screening
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Assay Development and High-Throughput Screening of Small Molecular c-Abl Kinase Activators

2011 Journal of Biomolecular Screening
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Discovery and Characterization of a Cell-Permeable, Small-Molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site

2011 Chemistry & Biology
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Pentathiepins and Trithianes from Two Lissoclinum Species and a Eudistoma sp.: Inhibitors of Protein Kinase C.

2010 ChemInform
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Process Validation and Screen Reproducibility in High-Throughput Screening

2009 Journal of Biomolecular Screening
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Studies on acyl pyrrolidine inhibitors of HCV RNA-dependent RNA polymerase to identify a molecule with replicon antiviral activity

2007 Bioorganic & Medicinal Chemistry Letters
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Citations (36)