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Paul M.J. McSheehy

St George's Hospital

32

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2527

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Continuous low-dose infusion of patupilone increases the therapeutic index in mouse and rat tumour models

2018 Anti-Cancer Drugs
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Evaluation of the mTOR inhibitor, everolimus, in combination with cytotoxic antitumor agents using human tumor models in vitro and in vivo.

2011 Anti-Cancer Drugs
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Quantified tumor t1 is a generic early-response imaging biomarker for chemotherapy reflecting cell viability.

2010 Clinical Cancer Research
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mTOR Inhibitor RAD001 (Everolimus) Has Antiangiogenic/Vascular Properties Distinct from a VEGFR Tyrosine Kinase Inhibitor

2009 Clinical Cancer Research
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Effects of the Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235 on the Tumor Vasculature: Implications for Clinical Imaging

2008 Cancer Research
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Applications of 19F‐NMR to Oncology

2007
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Minimally Invasive Pharmacokinetic and Pharmacodynamic Technologies in Hypothesis-Testing Clinical Trials of Innovative Therapies

2006 Journal of the National Cancer Institute
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Minimally invasive pharmacokinetic and pharmacodynamic technologies in hypothesis-testing clinical trials of innovative therapies: experience and recommendations

2006 Clinical Cancer Research
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Patupilone Induced Vascular Disruption in Orthotopic Rodent Tumor Models Detected by Magnetic Resonance Imaging and Interstitial Fluid Pressure

2005 Clinical Cancer Research
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Investigations in vivo of the effects of carbogen breathing on 5-fluorouracil pharmacokinetics and physiology of solid rodent tumours

2005 Cancer Chemotherapy and Pharmacology
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