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Josef Brueggen

Novartis

27

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2939

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Everolimus and PTK/ZK show synergistic growth inhibition in the orthotopic BL16/BL6 murine melanoma model.

2011 Cancer Chemotherapy and Pharmacology
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Abstract B246: NVP-BGJ398: A potent and selective inhibitor of the fibroblast growth factor receptor family.

2011 Molecular Cancer Therapeutics
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Discovery of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor Tyrosine Kinase

2011 Journal of Medicinal Chemistry
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Preclinical Antitumor Activity of the Orally Available Heat Shock Protein 90 Inhibitor NVP-BEP800

2010 Molecular Cancer Therapeutics
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Potent and Selective Inhibition of Polycythemia by the Quinoxaline JAK2 Inhibitor NVP-BSK805

2010 Molecular Cancer Therapeutics
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Preclinical anti-tumor activity of the orally available Hsp90 inhibitor NVP-BEP800

2010
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Abstract #5649: Pharmakokinetic/phamacodynamic relationship of the HSP90 inhibitor NVP-AUY922 in human xenografts and patients in a clinical Phase I trial

2009 Cancer Research
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NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models

2008 Breast Cancer Research
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Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity

2008 Molecular Cancer Therapeutics
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323 POSTER Patupilone, the novel microtubule stabilizer (MTS), retains activity against human colon tumour cells over-expressing P-gp in vitro and in vivo; comparison with other MTS

2007 Ejc Supplements
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