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Laurie Castonguay

Merck & Co.

9

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Highly Diastereoselective Diels-Alder Reaction Mediated by a Chiral Auxiliary Derived from Amino Indanol: The Role of Conformation on Diastereoselectivity.

2010 ChemInform
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Conformational Analysis and Receptor Docking of N-[(1S,2S)-3-(4-Chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (Taranabant, MK-0364), a Novel, Acyclic Cannabinoid-1 Receptor Inverse Agonist

2008 Journal of Medicinal Chemistry
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Potent Kv1.3 inhibitors from correolide—modification of the C18 position

2005 Bioorganic & Medicinal Chemistry Letters
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Bioisosteric replacement of anilide with benzoxazole: potent and orally bioavailable antagonists of VLA-4

2004 Bioorganic & Medicinal Chemistry Letters
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Binding of 2-aryl-4-(piperidin-1-yl)butanamines and 1,3,4-trisubstituted pyrrolidines to human CCR5: A molecular modeling-guided mutagenesis study of the binding pocket

2003 Biochemistry
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Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 3: a proposed pharmacophore model for 1-[N-(methyl)-N-(phenylsulfonyl)amino]-2-(phenyl)-4-[4-(substituted)piperidin-1-yl]butanes.

2001 Bioorganic & Medicinal Chemistry Letters
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The influence of ligand bite angle on the enantioselectivity of copper(II)-catalysed Diels–Alder reactions

1996 Chemical Communications
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The Influence of Ligand Bite Angle on the Enantioselectivity of Copper( II)-Catalyzed Diels-Alder Reactions.

1996 ChemInform
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Highly diastereoselective diels-alder reaction mediated by a chiral auxiliary derived from amino indanol: The role of conformation on diastereoselectivity

1995 Tetrahedron Letters
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