Highly Diastereoselective Diels-Alder Reaction Mediated by a Chiral Auxiliary Derived from Amino Indanol: The Role of Conformation on Diastereoselectivity.

Summary The oxazolidinone 2 derived from amino indanol 1 functions as a very efficient chiral auxiliary for the Diels-Alder reaction. The effect of conformation has been explored using a range of constrained phenyl glycinol analogues.