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Lu Liu

University of California, San Francisco

13

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428

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The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261

2006 Biochemistry
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Tryptophan 80 and leucine 143 are critical for the hydride transfer step of thymidylate synthase by controlling active site access.

2002 Biochemistry
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Production of a polyketide natural product in nonpolyketide-producing prokaryotic and eukaryotic hosts

1998 Proceedings of the National Academy of Sciences of the United States of America
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Contributions of orientation and hydrogen bonding to catalysis in Asn229 mutants of thymidylate synthase 1 1 Edited by I. A. Wilson

1998 Journal of Molecular Biology
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Contributions of orientation and hydrogen bonding to catalysis in Asn229 mutants of thymidylate synthase

1998 Journal of Molecular Biology
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Expression of a functional non-ribosomal peptide synthetase module in Escherichia coli by coexpression with a phosphopantetheinyl transferase

1997 Chemistry & Biology
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A Novel dCMP Methylase by Engineering Thymidylate Synthase

1997 Biochemistry
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Partitioning Roles of Side Chains in Affinity, Orientation, and Catalysis with Structures for Mutant Complexes: Asparagine-229 in Thymidylate Synthase †,‡

1996 Biochemistry
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Asparagine 229 Mutants of Thymidylate Synthase Catalyze the Methylation of 3-Methyl-2'-deoxyuridine 5'-Monophosphate †

1996 Biochemistry
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5-Fluoro-2′-deoxycytidine 5′-monophosphate is a mechanism-based inhibitor of thymidylate synthase

1994 Biochimica et Biophysica Acta
- Lu Liu
- Daniel V. Santi
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