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Kiyoshi Takasuna

Daiichi Sankyo

44

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372

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Reliable identification of heart disease in drug discovery using automated patch clamps: Benchmarking best practices and calibration criteria for improved proarrhythmic assessment

2021 Journal of Pharmacological and Toxicological Methods
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Discovery of DS-1971a, a Potent Selective NaV1.7 Inhibitor.

2020 Journal of Medicinal Chemistry
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Reliable identification of cardiac liability in drug discovery using automated patch clamp: Benchmarking best practices and calibration standards for improved proarrhythmic assessment

2020 Journal of Pharmacological and Toxicological Methods
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Electrophysiological evaluation of pentamidine and 17-AAG in human stem cell-derived cardiomyocytes for safety assessment

2019 European Journal of Pharmacology
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Comprehensive in vitro cardiac safety assessment using human stem cell technology (CSAHi–The second stage) –Ca2+ transient platform

2018 Journal of Pharmacological and Toxicological Methods
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Comprehensive in vitro cardiac safety assessment using human stem cell technology: Overview of CSAHi HEART initiative

2016 Journal of Pharmacological and Toxicological Methods
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Availability of intracellular Ca2+ imaging using iPS-induced cardiomyocytes as a new cardiac toxicity assessment

2015 Journal of Pharmacological and Toxicological Methods
- Tomoko Sakakura
- Kiyoshi Takasuna
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Estimation of Glomerular Filtration Rate in Cynomolgus Monkeys (Macaca fascicularis)

2014 Journal of Veterinary Medical Science
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Comparison of Renal Biomarkers with Glomerular Filtration Rate in Susceptibility to the Detection of Gentamicin-Induced Acute Kidney Injury in Dogs

2014 Journal of Comparative Pathology
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Which pathological condition is the most critical for drug-induced torsades de pointes?

2012 Journal of Pharmacological and Toxicological Methods
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