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Apollon Papadimitriou

Hoffmann-La Roche

17

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627

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Abstract 6698: A first-in-class SIK3 inhibitor, OMX-0370, effectively inhibits tumor growth in syngeneic tumor models, as single agent, by abolishing tumor resistance to immune-derived TNF

2020 Immunology
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Validation of a ligand-binding assay for active protein drug quantification following the ‘free analyte QC concept’

2016 Bioanalysis
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2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV): (Part 3 - LBA, biomarkers and immunogenicity).

2016 Bioanalysis
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2015 White Paper on recent issues in bioanalysis: focus on new technologies and biomarkers (Part 3 – LBA, biomarkers and immunogenicity)

2015 Bioanalysis
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Developability Assessment During the Selection of Novel Therapeutic Antibodies

2015 Journal of Pharmaceutical Sciences
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An ex vivo potency assay to assess active drug levels of a GLP-1 agonistic peptide during preclinical safety studies

2015 Bioanalysis
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Can LC–MS/MS and ligand-binding assays live in harmony for large-molecule bioanalysis?

2014 Bioanalysis
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A novel approach to investigate the effect of methionine oxidation on pharmacokinetic properties of therapeutic antibodies

2014 mAbs
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Structure-based prediction of asparagine and aspartate degradation sites in antibody variable regions.

2014 PLOS ONE
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Analytical FcRn affinity chromatography for functional characterization of monoclonal antibodies

2013 mAbs
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Citations (84)