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David J. Lloyd

Amgen

19

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1526

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Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor

2020 mAbs
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Anti-obesity effects of GIPR antagonists alone and in combination with GLP-1R agonists in preclinical models

2018 Science Translational Medicine
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Haploinsufficiency of the Insulin Receptor in the Presence of a Splice-Site Mutation in Ppp2r2a Results in a Novel Digenic Mouse Model of Type 2 Diabetes.

2016 Diabetes
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Pharmacologic Effects of FGF21 Are Independent of the “Browning” of White Adipose Tissue

2015 Cell Metabolism
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Pharmacological Targeting of Glucagon and Glucagon-Like Peptide 1 Receptors Has Different Effects on Energy State and Glucose Homeostasis in Diet-Induced Obese Mice

2011 Journal of Pharmacology and Experimental Therapeutics
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A Volumetric Method for Quantifying Atherosclerosis in Mice by Using MicroCT: Comparison to En Face

2011 PLOS ONE
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Antidiabetic effects of 11β-HSD1 inhibition in a mouse model of combined diabetes, dyslipidaemia and atherosclerosis

2009 Diabetes, Obesity and Metabolism
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Identification of three loci affecting HDL-cholesterol levels in a screen for chemically induced recessive mutations in mice

2009 Journal of Lipid Research
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New variants in the Enpp1 and Ptpn6 genes cause low BMD, crystal-related arthropathy, and vascular calcification.

2009 Journal of Bone and Mineral Research
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Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice

2009 Diabetes
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Citations (830)