Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor

Xiaoshan Min,Junming Yie,Jinghong Wang,Ben C. Chung,Ching-Shin Huang,Haoda Xu,Jie Yang,Liying Deng,Joanne Lin,Qing Chen,Christina Abbott,Caroline Gundel,Stephen A. Thibault,Tina Meng,Darren L. Bates,David J. Lloyd,Murielle M. Véniant,Zhulun Wang

Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor

2020

Xiaoshan Min
Junming Yie
Jinghong Wang
Ben C. Chung
Ching-Shin Huang
Haoda Xu
Jie Yang
Liying Deng
Joanne Lin
Qing Chen
Christina Abbott
Caroline Gundel
Stephen A. Thibault
Tina Meng
Darren L. Bates
David J. Lloyd
Murielle M. Véniant
Zhulun Wang

AbstractGlucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone involved in regulating glucose and lipid metabolism. GIP receptor (GIPR) antagonism is believed to offer therapeuti...

Keywords:

GIP receptor
Antagonism
Incretin Hormone
Antibody
Receptor
Biochemistry
Lipid metabolism
Molecular biology
Biology
Immune system
Glucose-dependent insulinotropic polypeptide
molecular mechanism

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