author-photo

Michelle Chen

Amgen

26

Papers

1684

Citations

Citation Trend

Filter By

Papers (19) Sort By

Journal Conference Others

GIPR antagonist antibodies conjugated to GLP-1 peptide are bispecific molecules that decrease weight in obese mice and monkeys

2021
Show All
- Source
- Cite
- Save
Citations (2)
Chronic glucose-dependent insulinotropic polypeptide receptor (GIPR) agonism desensitizes adipocyte GIPR activity mimicking functional GIPR antagonism.

2020 Nature Communications
Show All
- Source
- Cite
- Save
Citations (18)
FGF21 acts as a negative regulator of bile acid synthesis

2018 Journal of Endocrinology
Show All
- Source
- Cite
- Save
Citations (19)
FGF21 Is Not a Major Mediator for Bone Homeostasis or Metabolic Actions of PPARα and PPARγ Agonists

2017 Journal of Bone and Mineral Research
Show All
- Source
- Cite
- Save
Citations (35)
Abstract 128: Recombinant Lecithin Cholesterol Acyltransferase Generates Mature High Density Lipoprotein with Increased Capacity to Efflux Cholesterol via ABCG1 in Cynomolgus Monkeys

2015 Arteriosclerosis, Thrombosis, and Vascular Biology
Show All
- Source
- Cite
- Save
Citations (0)
Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 1. Discovery of a Novel Tool Compound for in Vivo Proof-of-Concept

2014 Journal of Medicinal Chemistry
Show All
- Source
- Cite
- Save
Citations (24)
Understanding the physical interactions in the FGF21/FGFR/β-Klotho complex: structural requirements and implications in FGF21 signaling.

2012 Chemical Biology & Drug Design
Show All
- Source
- Cite
- Save
Citations (66)
Lack of Overt FGF21 Resistance in Two Mouse Models of Obesity and Insulin Resistance

2012 Endocrinology
Show All
- Source
- Cite
- Save
Citations (131)
An apoA-I mimetic peptibody generates HDL-like particles and increases alpha-1 HDL subfraction in mice.

2012 Journal of Lipid Research
Show All
- Source
- Cite
- Save
Citations (16)
Synthesis and Evaluation of the Metabolites of AMG 221, a Clinical Candidate for the Treatment of Type 2 Diabetes.

2011 ACS Medicinal Chemistry Letters
Show All
- Source
- Cite
- Save
Citations (14)