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Jean Denis Docquier

University of Siena
University of Liège

142

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Anatomy of an extensively drug-resistant Klebsiella pneumoniae outbreak in Tuscany, Italy.

2021 Proceedings of the National Academy of Sciences of the United States of America
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1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity

2021 European Journal of Medicinal Chemistry
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4-Alkyl-1,2,4-triazole-3-thione analogues as metallo-β-lactamase inhibitors

2021 Bioorganic Chemistry
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Anatomy of an Extensively Drug Resistant Klebsiella pneumoniae Outbreak in Tuscany, Italy

2021 bioRxiv
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Amino Acid Replacement at Position 228 Induces Fluctuation in the Ω-Loop of KPC-3 and Reduces the Affinity against Oxyimino Cephalosporins: Kinetic and Molecular Dynamics Studies

2020 Catalysts
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4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors

2020 European Journal of Medicinal Chemistry
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Crystal Structure of the VIM-2 Acquired Metallo-beta-Lactamase in Complex with the thiazolecarboxylate inhibitor ANT2681

2020
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Crystal Structure of the VIM-2 Acquired Metallo-beta-Lactamase in Complex with Taniborbactam (VNRX-5133)

2020
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ANT2681: SAR studies leading to the identification of a metallo-β-lactamase inhibitor with potential for clinical use in combination with meropenem for the treatment of infections caused by NDM-producing Enterobacteriaceae

2020 ACS Infectious Diseases
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4-(N-Alkyl- and -Acyl-amino)-1,2,4-triazole-3-thione Analogs as Metallo-β-Lactamase Inhibitors: Impact of 4-Linker on Potency and Spectrum of Inhibition

2020
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