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Marc Lemonnier

Spanish National Research Council

21

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Virtual Screening Approach to Identifying a Novel and Tractable Series of Pseudomonas aeruginosa Elastase Inhibitors

2021 ACS Medicinal Chemistry Letters
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Novel Specific Metallo-ß-lactamase Inhibitor, ANT2681, Restores Meropenem Activity to Clinically Effective Levels Against NDM-Positive Enterobacterales.

2021 Antimicrobial Agents and Chemotherapy
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Virtual screening approach leading to the identification of a novel and tractable series of Pseudomonas aeruginosa elastase inhibitors

2021
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ANT2681: SAR studies leading to the identification of a metallo-β-lactamase inhibitor with potential for clinical use in combination with meropenem for the treatment of infections caused by NDM-producing Enterobacteriaceae

2020 ACS Infectious Diseases
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Discovery of ANT3310, a Novel Broad-Spectrum Serine β-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and Acinetobacter baumannii.

2020 Journal of Medicinal Chemistry
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A Common Origin for the Bacterial Toxin-Antitoxin Systems parD and ccd, Suggested by Analyses of Toxin/Target and Toxin/Antitoxin Interactions

2012 PLOS ONE
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Novel Escherichia coli RF1 mutants with decreased translation termination activity and increased sensitivity to the cytotoxic effect of the bacterial toxins Kid and RelE

2009 Molecular Microbiology
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Interactions Between the Toxin Kid of the Bacterial parD System and the Antitoxins Kis and MazE

2007 Proteins
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Model for RNA Binding and the Catalytic Site of the RNase Kid of the Bacterial parD Toxin-Antitoxin System

2006 Journal of Molecular Biology
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RNase/Anti-RNase Activities of the Bacterial parD Toxin-Antitoxin System

2005 Journal of Bacteriology
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Citations (46)