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Robert L. Smith

Merck & Co.

30

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1207

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2-substituted piperazines as constrained amino acids. Application to the synthesis of potent, non carboxylic acid inhibitors of farnesyltransferase.

1996 Journal of Medicinal Chemistry
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Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor

1993 Science
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Non-peptide fibrinogen receptor antagonists. 1. Discovery and design of exosite inhibitors

1992 Journal of Medicinal Chemistry
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L‐662,583 is a topically effective ocular hypotensive carbonic anhydrase inhibitor in experimental animals

1990 British Journal of Pharmacology
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A process for the preparation of antihypercholesterolemic compounds.

1987
- Robert L. Smith
- Gerald E. Stokker
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Synthesis and biological activity of 3-amino-5-(3,5-diamino-6-chloropyrazin-2-yl)-1,2,4-oxadiazole. An amiloride prodrug

1986 Journal of Medicinal Chemistry
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Chapter 9. Antiglaucoma Agents

1985 Annual Reports in Medicinal Chemistry
- Michael F. Sugrue
- Robert L. Smith
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Prostaglandin isosteres. 2. Chain-modified thiazolidinone prostaglandin analogues as renal vasodilators.

1983 Journal of Medicinal Chemistry
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2-(Aminomethyl)phenols, a new class of saluretic agents. 6. Effects of N,O-spiroannulation and subsequent quaternization.

1983 Journal of Medicinal Chemistry
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2-(Aminomethyl)phenols, a new class of saluretic agents. 5. Fused-ring analogues.

1983 Journal of Medicinal Chemistry
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Citations (90)